Suman Shrestha

PhD Candidate | Landauer Sr. Fellow

Radiation Physics, Division of Radiation Oncology
University of Texas MD Anderson Cancer Center
 

Chair | Working  Group on Communications

International Society of Radiation Epidemiology and Dosimetry [ISoRED]

Chair | Work Group on Student and Trainee Research
American Association of Physicist in Medicine [AAPM] 

Office Phone:

713-792-3843

Email:

sshrestha1@mdanderson.org       inspirephysics@gmail.com

Office Address:

8060 El Rio Street | Unit 605 | ERD 1.221B

Houston, TX 77054

BACKGROUND

                                         


        Mr. Shrestha is a pediatric cancer researcher with a focus on therapy-related cardiovascular disease. He is a doctoral research fellow in the medical physics program at MD Anderson Cancer Center and UTHealth Graduate School of Biomedical Sciences. He is a scientist in training and serves as the principal or co-investigator on multiple research projects funded by the UT Health and Childhood Cancer Survivor Study (CCSS) and other funding agencies. His goal is to become an independent researcher, licensed medical physicist, and a tenured professor. He plans to contribute to health care reform in developing countries. He is committed to producing the next generation of medical physicists, pediatric health scientists and leads a CCSS-funded research project within Late Effects Research Group, MD Anderson Cancer Center. A major focus of Mr. Shrestha's research and clinical interest has been on developing models to predict the risk of late cardiac disease from contemporary radiotherapy techniques. Data from this study could be used to establish treatment protocols and inform screening strategies for current patients and future survivors of childhood cancer. The human health implications of this work are the reduction of severe and disabling cardiac disease in future survivors of childhood cancer. He has been recognized for his work by many medical associations and has subsequently been emerging as an important voice in the field of late effects of radiation therapy. He currently serves as the Chairman of work-group on student and trainee research (WGSTR) within American Association of Physicists in Medicine (AAPM) and also serves as the Chairman of  the working group on communications (WGC) in International Society of Radiation Epidemiology and Dosimetry (ISoRED). 

EDUCATION 
 
2018-Present

Doctor of Philosophy
Medical Physics

GPA: 4.00

UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER UT HEALTH GSBS

PhD Project: "Risk Score Algorithm to Predict Individual Risk of Future Serious Late Cardiovascular Disease that includes Dose and Dose Volume Metrics for the Whole Heart and Heart Substructures"
Advisor: Prof. Rebecca M. Howell, PhD, DABR, FAAPM 

2015-2018

Master's Degree
Medical Physics

GPA: 3.85

LOUISIANA STATE UNIVERSITY

Thesis Title: "Analytical Models of Neutron Spectral Fluence, Kerma and Absorbed Dose For ProtonTherapy" 
Advisor: Prof. Wayne D. Newhauser, PhD, DABR, FAAPM, FAAAS 

2010-2013

Master's Degree
Physics

TRIBHUVAN UNIVERSITY

Central Department of Physics [Best Gradaute School in Nepal]
Double Major: Advanced Solid State Physics and Biomedical Physics

2006-2010

Bachelor's Degree
Physics

TRIBHUVAN UNIVERSITY

Major: Physics  | Minors: Chemistry & Math

BOARD CERTIFICATION
2017

ABR I

CERTIFICATE IN THERAPEUTIC MEDICAL PHYSICS

American Board of Radiology in Medical Physics, Part I , Complete

EXPERIENCE & SERVICE
 
2018-Present

Graduate Research Assistant

MD ANDERSON CANCER CENTER & UTHEALTH GRADUATE SCHOOL OF BIOMEDICAL SCIENCES

As a member of Late Effects Research Group, his focus has been developing a new anatomy based cardiac model with substructure definition to facilitate cardiac toxicity research. He is devising computational organ models and novel dosimetry methodologies  for patients who have undergone contemporary radiation therapy. This will enable unique and unprecedented late-effects studies. Data from such studies will significantly improve the understanding of impact of advanced radiotherapy on late effects.

2017-2018

Graduate Research Assistant

LOUISIANA STATE UNIVERSITY

At LSU, his research focused on developing models to accurately calculate the stray radiation in proton therapy, i.e., dose outside the treatment beam due to neutron contamination. The goal of my thesis project was to create a physics-based model, generally applicable, and computationally efficient to enable routine clinical calculations of the many sources of stray neutron dose. This information will enable accurate risk calculations in both retrospective and prospective cases. 

2015-2017

Graduate Teaching Assistant

LOUISIANA STATE UNIVERSITY

He had worked as TA for graduate course MEDP 7121: Radiation Biology. Taught undergraduate physics lab, Phys-2109: Introductory Electricity and Magnetism Lab and general physics course Phys-2002: Electricity and Magnetism, general physics course. Responsibilities included teaching basic physics principles, instructing during lab, grading their reports and writing and grading Finals.

2014-2015

Lecturer in Physics
Academic Advisor 

NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY, NEPAL

Responsibilities as lecturer included teaching lectures in Physics and instructing students in laboratory ,question setting, grading, conducting conferences and seminars etc. Also responsible for advising and counselling of students in science group which involved conducting meetings with guardians, one to one session with students, getting feedback from other professors etc.

HONORS & AWARDS
 

2021                   Virtual Conference Award, The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical                               Sciences

2021                   ACR Medical Physics Graduate Scholarship, American College of Radiology (ACR)

 

2021                   Winner (1st Place) - MedPhys SLAM Competition, South West American Association of Physicist in Medicine SWAAPM

2021                   Best Physics Publication, Department of Radiation Physics, MD Anderson Cancer Center, Awarded the MD Anderson                                       Cancer Center Radiation Physics Publication of the Month (Nov/Dec 2020) for outstanding research.

2020                   Robert S. Landauer, Sr. Fellowship in Health Physics 2020-2021, Health Physics Society

2020                   Health Physics Society Travel Grant 2021, Health Physics Society

2020                   Chair-Elect (2021), Vice-Chair (2020), Working Group on Student and Trainee Research, American Association of Physicist in                             Medicine (AAPM)
 

2020                   Radiation Oncology Commendation, Section of Outreach Physics, Division of Radiation Oncology, UT MD Anderson                                       Cancer Center

2020                   UT Health Science Center, Graduate School of Biomedical Sciences International Travel Award, The University of Texas MD                             Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences

2020                   Best Poster Award [Winner], 2nd Author, Southwest Regional Chapter of American Association of Physicist in Medicine

 

2020                   Best Poster Award [2nd Runner Up], Southwest Regional Chapter of American Association of Physicist in Medicine

2019                   Sylvan Rodriguez Foundation Scholarship honoring George M. Stancel, Ph.D. 2019-2020, UTHealth GSBS

2019                   NCI International Fellowship [ISORED], National Cancer Institute, Maryland, USA

2019                   Marilyn and Frederick R. Lummis, Jr. M.D., Fellowship in the Biomedical Sciences 2019-2020, UTHealth GSBS
 

2019                   UT Health Science Center, Graduate School of Biomedical Sciences Travel Award, The University of Texas MD Anderson                                 Cancer Center UTHealth Graduate School of Biomedical Sciences
 

2019                   Expanding Horizons Travel Grant Award, American Association of Physicist in Medicine
 

2018                   Childhood Cancer Survivor Study (CCSS) Career Development Award 2018-2019, St. Jude Children’s Research Hospital
 

2018                   Health Physics Society Travel Grant [Schedule Conflict with Thesis Defense]
 

2017                   Health Physics Society Travel Grant, Awarded and attended the HPS Annual Meeting in Raleigh, NC Health Physics Society

2010                   Merit List Student, Central Department of Physics, Tribhuvan University, Best Physics Graduate School in Nepal
 

2005-09             Merit Based Scholarship for Deserving Student, Awarded during Proficiency Certificate Level and Bachelor’s Degree, Amrit                            Science College, Tribhuvan University, Nepal
 

2004                  Excellence in Academia-Top 3 Student, Vishwa Niketan Higher Secondary School, Nepal
 

2004                 Jana-Kalyan Scholarship for Poor and Deserving Student, Jana-Kalyan Foundation, Nepal

PROFESSIONAL MEMBERSHIPS

International Training and Research Coordination Subcommittee (ITRCS)

Guest Member, 01/2020 – 12/2020

European Society of Radiation Oncology (ESTRO)

Student Member, 2020 – Present

Student and Trainees Subcommittee (STSC)

WGSTR Liaison, 2020 – Present

Work Group on Student and Trainee Research (WGSTR)

Chair 2021- Present, Vice-Chair 2019-20, Member, 2019 – Present

American College of Radiology (ACR)

National Training Physicist , 2019 – Present

American Heart Association (AHA)

Student Member, 2019 – Present


Council on Epidemiology and Prevention

Membership through AHA, 2019 – Present

Work Group on Radiation Dosimetry (WGRD)

Guest Member (Non-voting), 07/2019 – 12/2020

 

American Society of Radiation Oncology

Student Member, 2019 – Present

Radiation Research Society (RRS)

Scholar in Training, 2017 – Present

 

Radiological Society of North America (RSNA)

Student Member, 2017 – Present

 

American Nuclear Society (ANS)

Student Member, 2016 – 2018

 

Health Physics Society (HPS)

Student Member, 2016 – Present

 

American Association of Physicist in Medicine (AAPM)

Student Member, 2015 – Present

 
  • Google Scholar Link
PEER REVIEWED MANUSCRIPTS


  1. Shrestha S., Bates J.E., Liu Q., Smith S., Oeffinger K., Chow E., Gupta A.C., Owens C.A., Constine L.S., Hoppe B.S., Leisenring W., Qiao Y., Weathers R.E, Court L.E., Pinnix C.C., Kry S.F., Mulrooney D., Armstrong G.T., Yasui Y., Howell R.M., “Radiation Therapy Related Cardiovascular Risk in Childhood Cancer Survivors: Updated Analysis from the Childhood Cancer Survivor Study” Accepted 08/19/2021 Radiotherapy Oncology. 
     

  2. Shrestha, S., Gupta, A.C., Bates, J., Lee, C., Owens, C.A., Hoppe, B., Constine, L., Smith, S., Qiao, Y., Weathers, R., Yasui, Y., Court, L., Paulino, A.C., Pinnix, C., Kry, S., Followill, D.. Howell, R, “Development and Validation of Computed Tomography Based (Age-Scalable) Cardiac Model with Substructure for Dosimetry in Late Effects Studies” Radiotherapy and Oncology , Radiotherapy and Oncology (2020), doi: https://doi.org/10.1016/j.radonc.2020.10.017
     

  3. Gupta, A.C., Shrestha, S., Smith, S., Qiao, Y., Weathers, R., Owens, C., Kry, S.F., Howell, R.M. “Development of an Age-Scalable 3D Computational Phantom in DICOM Format in Commercial Treatment Planning System for Use in Late Effects Studies” , 2020 Biomed. Phys. Eng. Express 6 065004
     

  4. Newhauser, W.D., Schneider, C., Wilson, L., Shrestha, S., and Donahue, W., (2017). “A review of analytical models of stray radiation exposures from photon- and proton-beam radiotherapies.” Radiation Protection Dosimetry, Volume 180, Issue 1-4, August 2018, Pages 245–251.

    First Authored

  1. Shrestha, S. “"Relationship Between Coronary Artery Radiation Doses and Risk of Late Coronary Artery Disease: A Report from the Childhood Cancer Survivor Study (CCSS)" AAPM 2021, [Oral Presentation]
     

  2. Shrestha, S. “Risk Score Algorithm to Predict Individual Risk of Future Serious Late Cardiovascular Disease
    American Association of Physicist in Medicine (AAPM), Med Phys Oral Slam, AAPM 2021 [Oral Presentation]
     

  3. Shrestha, S.” The impact of Expanding Horizons Grant and WGSTR Initiatives in Research Progress of AAPM Trainees” AAPM 2021, Expanding Horizon Sessions, AAPM 2021, [Oral Presentation],
     

  4. Shrestha, S.” Development of Risk Score Algorithm to Predict Individual Risk of Future Serious Late Cardiovascular Disease” SWAAPM 2021, Med Phys Slam, [Oral Presentation]
     

  5. Shrestha, S. et al.” Impact of Enhanced CT-based Heart Model on Estimating Radiation Therapy Related Late-Onset Cardiac Disease in the Childhood Cancer Survivor Study” Med Phys. 2020; 47; 6: e464 [Blue-ribbon, Snap Oral]
     

  6. Shrestha, S. et al., “Development and inter-variability study of computed tomography based computational cardiac models for cardiac dosimetry in late effects studies” International Society for Radiation, Epidemiology and Dosimetry (ISORED) 2020, Sitges, Spain [Short Oral + Discussion + Poster presentation]
     

  7. Shrestha, S. et al., “Development of CT-based cardiac model with substructure for dosimetry in late effects studies” Radiotherapy and Oncology, Volume 153, 163 - 171, ESTRO Congress 2020 [Short Oral + Discussion + Poster]
     

  8. Shrestha, S. et al., “Computed tomography based computational cardiac models for dosimetry in late effects studies” South West American Association of Physicist in Medicine, SWAAPM 2020 [Poster Presentation]
     

  9. Shrestha, S., Howell, R.M. “North American Symposium on Late Effects After Childhood Cancer (NASLCC), CCSS & IGHG Meeting: Expanding Horizon Grant Awardees Perspective”, AAPM 2020, [Short Oral + Poster]
     

  10. Shrestha, S., Howell, R.M. “Status of an enhanced heart model with substructures for cardiac dosimetry for late effects studies”, ASTRO Pre-conference Physician Meet, September 14, 2019; Chicago, Michigan [Oral Presentation]
     

  11. Shrestha, S. et al., “Development of an enhanced heart model with substructures for cardiac dosimetry for late effects studies”, Med Phys. 2019; 46; 6: e313 [Discussion Session and Poster Presentation]  
     

  12. Shrestha, S., "Analytical Models of Neutron Spectral Fluence, Kerma and Absorbed-Dose for Proton Therapy" (2018). LSU Master's Theses. 4781.

    Co-authored
     

  13. Bates J, Shrestha, S. et al. “Impact of Cardiac Substructure Dosimetry on Late Cardiac Risk: A Report from the Childhood Cancer Survivor Study (CCSS): A Report from Childhood Cancer Survivor Study (CCSS): ASTRO 2021 [Oral Presentation]
     

  14. Bates J, Shrestha, S. et al. “Impact of Cardiac Substructure Dosimetry on Arrhythmia Risk in Long Term Survivors of Childhood Cancer: A Report from Childhood Cancer Survivor Study (CCSS): ESTRO 2021 [Oral Presentation]
     

  15. Owens C., Riguad B., Ludmir E., Gupta, A., Shrestha, S. et al. “From Person-Specific to Population-Based Colorectal Models: An Age-Scalable Computational Anatomical Colorectal Model for Radiation Dosimetry in Late Effects Studies of Childhood Cancer Survivors” AAPM 2021, [Oral Presentation]
     

  16. Gupta A., Owens C., Netherton, T., Lee, C., Shrestha, S. et al. “Implementation and Validation of Non-Uniform Body Region Specific 3D Age Scaling Factors (ASF) to Scale Whole-Body Computed Tomography (CT) Anatomy to Any Arbitrary Age” AAPM 2021, [ Discussion + Poster]
     

  17. Bates J, Shrestha, S. et al. “Low Dose Radiation to Cardiac Substructures and Late Onset Cardiac Disease: A Report from the Childhood Cancer Survivor Study (CCSS)” ASCO 2021, [ Discussion + Poster]
     

  18. A Gupta, C Owens, S Shrestha et al.” Investigation on the use of our 3D age scaling factors/functions (ASF) to scale whole-body regions to any arbitrary age” Med Phys. 2020; 47; 6: e806-e807 [E-Poster]
     

  19. C Owens*, A Gupta, S Shrestha et al. “Development of an Age-Scalable Colon Model with Substructures for Colon Radiation Therapy Dosimetry in Large Pediatric Cohorts for Late-Effects Studies” Med Phys. 2020; 47; 6: e743-e744 [E-Poster]
     

  20. A Gupta, C Owens, S Shrestha et al. “Development of Patient Height-Specific 3D Age-Scaling Factors to Generate DICOM Computational Phantoms for Retrospective Late-Effects Studies” Med Phys. 2020; 47; 6: e746 [E-Poster]
     

  21. Owens, C.*, Gupta, A.C., Shrestha, S., et al. “Development of a colon model for colon dosimetry in late effect studies” International Society for Radiation, Epidemiology and Dosimetry (ISORED) 2020, Sitges, Spain [Short Oral + Discussion + Poster]
     

  22. Gupta, A.C., Qiao, Y., Shrestha, S. et al. “On the Implementation and Validation of 3D Computational Pediatric Phantoms in Commercial TPS” Radiotherapy and Oncology, Volume 152, S702 - S703, ESTRO Congress 2020 [Poster]
     

  23. Gupta, A.C., Shrestha, S. et al., “An age scalable 3D computational phantom in DICOM standard for late effects studies”, South West American Association of Physicist in Medicine, SWAAPM 2020 [Poster Presentation]
     

  24. Gupta, A.*, Ying, Q., Lee, C., Ditty, C., Smith, S., Weathers, R., Shrestha, S. et al., “Implementation of 3D Computational Human Phantoms in RayStation for Retrospective Studies in Late Effects”. Med Phys. 2019; 46; 6: e586 [E-Poster]
     

  25. Hernandez, S.*, Weathers, R., Gupta, A., Shrestha, S et al. “Liver Dose Estimation for a PENTEC Late Effects Study”. Med Phys. 2019; 46; 6: e585 [E-Poster Presentation]
     

  26. Newhauser, W.D., Schneider, C., Wilson, L., Shrestha, S., Lis, M. and Donahue, W., (2017). Modeling of risk of secondary cancer from radiotherapy, 13th NEUDOS Symposium; May 14-16,2017; Krakow, Poland [Oral Presentation]

PEER REVIEWED ABSTRACTS
RESEARCH SUPPORT
 

PRESENT

Title:                                      Influence of Radiotherapy Dose to Cardiac Substructures on Cardiac Risk in Long-term Survivors of Childhood                                                       Cancer

Study Source:                       Childhood Cancer Survivor Study (co-PIs': Bates & Howell)

Role:                                      Investigator

Link:                                       https://ccss.stjude.org/content/dam/en_US/shared/ccss/documents/aoi/concept-proposal%2019-16.pdf

Title:                                      Risk Score Algorithm to Predict Individual Risk of Future Serious Late Cardiovascular Disease that includes Dose                                                   and Dose Volume Metrics for the Whole Heart and Heart Substructures

Study Source:                       Childhood Cancer Survivor Study (co-PIs': Howell & Mulrooney)

Role:                                      Investigator

Link:                                       https://ccss.stjude.org/content/dam/en_US/shared/ccss/documents/aoi/20191115

PAST

Title:                                      Enhancing heart model of current CCSS age-specific computational phantoms by defining cardiac substructures                                                   and dose reconstruction

Funding Source:                   Childhood Cancer Survivor Study Career Development Award, NCI

Role:                                      Principal Investigator (Trainee)
Link:                                       https://ccss.stjude.org/career-development-award.html

Title:                                      Therapy Related Cardiac Risk in Childhood Cancer Survivors

Funding Source:                   UT Health Graduate School of Biomedical Sciences, Marilyn and Frederick R. Lummis, Jr. M.D. Fellowship

Role:                                      Principal Investigator (Fellow)

Link:                                       https://gsbs.uth.edu/current-students/awards-and-funding-opportunities/scholarships-and-fellowships.htm

MEDIA MENTIONS

  • Shrestha's PhD Research praised on world stage; Cardiac Model Praised Physics World
     

  • Shrestha awarded Landauer Sr. Fellowship: HPS
     

  • Physics in the pandemic: Physics World Shrestha
     

  • Shrestha receives Career Development Award , GSBS  
     

  • Shrestha awarded CCSS Career Development Award, St. Jude
     

  • Shrestha receives Marilyn and Frederick R. Lummis, Jr. M.D., Fellowship GSBS  
     

  • Shrestha awarded Sylvan Rodrigue Sylvan Rodriguez Foundation Scholarship honoring George M. Stancel, Ph.D., GSBS
     

  • Shrestha Expanding Horizon Grant Experience, AAPM Newsletter (Page 77-78)